Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510559 | 0.88 | HDAC1 (0.79) | HDAC1CYP3A4HDAC3HDAC4HDAC7 | |
| SCHEMBL6511431 | 0.81 | HDAC1 (0.46) | HDAC1MAPTRAB9AKMT2AFAAH | |
| SCHEMBL6508309 | 0.81 | HDAC1 (0.84) | HDAC1DRD4CYP3A4 | |
| SCHEMBL6509908 | 0.80 | HDAC1 (0.54) | HDAC1DRD4KMT2AHDAC3HDAC4 | |
| SCHEMBL6507596 | 0.77 | HDAC1 (1.00) | HDAC1CYP3A4 | |
| SCHEMBL6507898 | 0.74 | HDAC1 (0.56) | HDAC1DRD4MAPTRAB9AKMT2A | |
| SCHEMBL6509841 | 0.73 | HDAC1 (0.46) | HDAC1KMT2AKDM4E | |
| SCHEMBL1123563 | 0.73 | MAPT (0.68) | DRD4MAPTRAB9AKMT2AKDM4E | |
| SCHEMBL6533816 | 0.73 | RAB9A (0.41) | HDAC1MAPTRAB9AFAAHHDAC3 | |
| SCHEMBL6507551 | 0.72 | HDAC1 (0.59) | HDAC1DRD4RAB9AKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |