Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511431 | 0.93 | HDAC1 (0.46) | HDAC1TSHRKDM4EALDH1A1ATM | |
| SCHEMBL6510292 | 0.91 | HDAC1 (0.59) | HDAC1ACKR3 | |
| SCHEMBL6513490 | 0.83 | TSHR (0.48) | HDAC1TSHRKDM4EALDH1A1ATM | |
| SCHEMBL6509983 | 0.79 | HDAC1 (0.76) | HDAC1 | |
| SCHEMBL6507970 | 0.76 | HDAC1 (0.52) | HDAC1NR4A2KDM4EALDH1A1ACKR3 | |
| SCHEMBL8293231 | 0.73 | HDAC1 (0.62) | HDAC1KDM4EKMT2A | |
| SCHEMBL14569771 | 0.72 | TSHR (0.69) | TSHRNR4A2KDM4EALDH1A1ATM | |
| SCHEMBL6533816 | 0.72 | RAB9A (0.41) | HDAC1TSHRKDM4EALDH1A1 | |
| SCHEMBL6531527 | 0.72 | HDAC1 (0.50) | HDAC1ACKR3 | |
| SCHEMBL17682060 | 0.71 | TSHR (0.81) | TSHRKDM4EALDH1A1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |