Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18784932 | 0.88 | TSHR (0.51) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL18789074 | 0.82 | TDP1 (0.59) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL1068908 | 0.78 | TDP1 (0.50) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL18672275 | 0.78 | VCAM1 (0.50) | TDP1MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL1065521 | 0.78 | TDP1 (0.53) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL29217568 | 0.76 | TDP1 (0.60) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL1063282 | 0.75 | TDP1 (0.50) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL6209524 | 0.75 | TDP1 (0.50) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL31715931 | 0.75 | VCAM1 (0.59) | TDP1TSHRMAPTALDH1A1LMNA | |
| SCHEMBL1068675 | 0.75 | VCAM1 (0.59) | TDP1TSHRMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030704-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |