Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.78 |
| ▸ | CTSL | P07711 | 7/20 | 0.66 |
| ▸ | CTSB | P07858 | 5/20 | 0.66 |
| ▸ | CTSF | Q9UBX1 | 5/20 | 0.66 |
| ▸ | CTSV | O60911 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288060 | 0.89 | CTSK (0.81) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL8290035 | 0.89 | CTSK (0.65) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL11981467 | 0.86 | CTSK (0.61) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL8433997 | 0.86 | CTSK (0.61) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL8295393 | 0.85 | CTSK (0.58) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL8296643 | 0.84 | CTSK (0.58) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL14350320 | 0.84 | CTSK (0.66) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL8295817 | 0.84 | CTSK (0.57) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL11981448 | 0.84 | CTSK (0.76) | CTSKCTSLCTSBCTSFCTSV | |
| SCHEMBL11981450 | 0.84 | CTSK (0.76) | CTSKCTSLCTSBCTSFCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021487-A1 | CATHEPSIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2005-03-10 | — | — | WO | disclosed |