Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296724 | 0.79 | ALDH1A1 (0.47) | ALDH1A1RAB9APYGLPKMSIGMAR1 | |
| SCHEMBL8294310 | 0.76 | ALDH1A1 (0.45) | ALDH1A1DPP4PYGLPKMSIGMAR1 | |
| SCHEMBL18969627 | 0.75 | CCR5 (0.49) | ALDH1A1RAB9APKMSIGMAR1KMT2A | |
| SCHEMBL7129642 | 0.74 | ALDH1A1 (0.59) | ALDH1A1RAB9APKMSIGMAR1KMT2A | |
| SCHEMBL756916 | 0.73 | ALDH1A1 (0.36) | ALDH1A1DPP4DPP8DPP9PKM | |
| SCHEMBL8296810 | 0.73 | ALDH1A1 (0.46) | ALDH1A1PYGLPKMSIGMAR1KMT2A | |
| SCHEMBL8294299 | 0.73 | ALDH1A1 (0.50) | ALDH1A1PYGLPKMSIGMAR1KMT2A | |
| SCHEMBL4405382 | 0.73 | ALDH1A1 (0.43) | ALDH1A1RAB9APYGLPKMKMT2A | |
| SCHEMBL3039993 | 0.73 | EPHX1 (0.49) | ALDH1A1RAB9APYGLPKMKMT2A | |
| SCHEMBL4248932 | 0.72 | ALDH1A1 (0.41) | ALDH1A1PYGLPKMSIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |