Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293676 | 0.93 | HDAC1 (0.44) | HDAC1HDAC8HDAC6TLR9TLR8 | |
| SCHEMBL8294919 | 0.85 | HDAC1 (0.45) | HDAC1HDAC8HDAC6TLR9TLR8 | |
| SCHEMBL8293659 | 0.83 | L3MBTL1 (0.40) | DPP7DPP4KCNH2DPP8ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6532979 | 0.81 | DGAT1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL6532983 | 0.81 | DGAT1 (0.46) | — | |
| SCHEMBL8294350 | 0.79 | ADAMTS7 (0.43) | HDAC1HDAC6DPP7DPP4KCNH2 | |
| Hydrochloric Acid SCHEMBL6809246 | 0.79 | HDAC3 (0.47) | HDAC1 | |
| Hydrochloric Acid SCHEMBL6809256 | 0.77 | DPP7 (0.38) | DPP7DPP4KCNH2DPP8TGM2 | |
| SCHEMBL8293660 | 0.76 | GAA (0.42) | DPP7DPP4DPP8ALDH1A1DPP9 | |
| SCHEMBL8292700 | 0.75 | HDAC1 (0.42) | HDAC1DPP7DPP4KCNH2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019168-A2 | FLUORINATED LYSINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-03-03 | — | — | WO | disclosed |