Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022120 | 0.90 | GLS (0.49) | GLSKDM4EPKMLMNAMEN1 | |
| SCHEMBL8294658 | 0.89 | GLS (0.49) | GLSKDM4EPKMLMNAMEN1 | |
| SCHEMBL1020384 | 0.87 | MEN1 (0.53) | GLSKDM4ELMNAMEN1KMT2A | |
| SCHEMBL30525131 | 0.87 | MEN1 (0.53) | GLSKDM4ELMNAMEN1KMT2A | |
| SCHEMBL4836517 | 0.87 | CYP2D6 (0.60) | GLSKDM4ELMNAMEN1KMT2A | |
| SCHEMBL8616309 | 0.87 | GLS (0.50) | GLSKDM4ELMNAMEN1KMT2A | |
| SCHEMBL12954829 | 0.86 | GLS (0.47) | GLSMEN1KMT2ATBK1ACKR3 | |
| SCHEMBL23014291 | 0.85 | KDM4E (0.52) | GLSKDM4EPKMLMNAMEN1 | |
| SCHEMBL29733707 | 0.85 | KDM4E (0.52) | GLSKDM4EPKMLMNAMEN1 | |
| SCHEMBL1020065 | 0.85 | PKM (0.47) | GLSKDM4EPKMTBK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023812-A2 | PIPERAZINES AS OXYTOCIN AGONISTS | FERRING B.V. (NL) | 2005-03-17 | — | — | WO | disclosed |