Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294657 | 0.89 | GLS (0.50) | GLSABCB1TBK1CYP2D6CYP2C9 | |
| SCHEMBL30525131 | 0.85 | MEN1 (0.53) | GLSTBK1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL1020384 | 0.85 | MEN1 (0.53) | GLSTBK1CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL4836517 | 0.85 | CYP2D6 (0.60) | GLSABCB1CYP2D6CYP2C9MEN1 | |
| SCHEMBL8616309 | 0.85 | GLS (0.50) | GLSTBK1CYP2D6CYP2C9MEN1 | |
| SCHEMBL5570335 | 0.85 | GLS (0.49) | GLSKDM1ATBK1CYP2D6CYP2C9 | |
| SCHEMBL1022120 | 0.83 | GLS (0.49) | GLSTBK1MEN1KMT2ALMNA | |
| SCHEMBL5571027 | 0.82 | FAAH (0.56) | GLSTBK1CYP2D6CYP2C9MEN1 | |
| SCHEMBL4837787 | 0.80 | GLS (0.54) | GLSKDM1ATBK1MEN1KMT2A | |
| SCHEMBL8540779 | 0.80 | ALDH1A1 (0.63) | GLSKDM1ACYP2D6CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023812-A2 | PIPERAZINES AS OXYTOCIN AGONISTS | FERRING B.V. (NL) | 2005-03-17 | — | — | WO | disclosed |