Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349959 | 0.80 | RAB9A (0.59) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL2161557 | 0.76 | RAB9A (0.57) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL10906842 | 0.75 | RAB9A (0.65) | RAB9ANPC1PTPN1HTR7PLOD2 | |
| SCHEMBL4242598 | 0.75 | RAB9A (0.53) | RAB9ANPC1PTPN1KCNQ3KCNQ2 | |
| SCHEMBL5379828 | 0.74 | RAB9A (0.59) | RAB9ANPC1PTPN1KCNQ3KCNQ2 | |
| SCHEMBL5302445 | 0.73 | GABRA5 (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL8302443 | 0.73 | RAB9A (0.54) | RAB9ANPC1PTPN1KCNQ3KCNQ2 | |
| SCHEMBL9661934 | 0.72 | RAB9A (0.66) | RAB9ANPC1PTPN1CTNNB1WNT3A | |
| SCHEMBL4554615 | 0.72 | CDK2 (0.42) | LMNA | |
| SCHEMBL8296405 | 0.70 | RAB9A (0.62) | RAB9ANPC1PTPN1CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508469-B1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1999-03-03 | — | — | EP | disclosed |
| US-5493024-A | 1,2-DIARYL-2-PROPEN-1-ONE CHEMICAL INTERMEDIATE COMPOUND | DOWELANCO (US) | 1996-02-20 | — | — | US | disclosed |
| US-5324837-A | 3,4-disubstituted-4,5-dihydro-1H-pyrazoles and a method of preparation | DOWELANCO (US) | 1994-06-28 | — | — | US | disclosed |
| US-5250532-A | Moths. termites | DOWELANCO (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0508469-A1 | 3,4,N-Trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insecticides | DOWELANCO (US) | 1992-10-14 | — | — | EP | disclosed |