Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 9/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19342800 | 0.89 | LTB4R2 (0.63) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL25964113 | 0.86 | LTB4R2 (0.66) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2364 | 0.86 | LTB4R2 (0.80) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2365 | 0.86 | LTB4R2 (0.80) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL17946059 | 0.85 | LTB4R2 (0.69) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL19236573 | 0.84 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL683480 | 0.83 | LTB4R2 (0.75) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL18406103 | 0.82 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL20694580 | 0.82 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8344867 | 0.82 | LTB4R2 (0.47) | LTB4R2AGTR1ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3109241-B1 | METHOD OF REFINING VALSARTAN COMPRISING MORE THAN 10% D-ISOMERS | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2019-04-17 | — | — | EP | disclosed |
| EP-2116548-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | Novartis AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2005014602-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |