Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293311 | 0.86 | TSHR (0.50) | HPGDKDM4EPTGS1PTGS2 | |
| SCHEMBL25016679 | 0.84 | OPRK1 (0.51) | OPRK1SLC6A4SLC6A2SLC6A3HPGD | |
| SCHEMBL14037612 | 0.82 | SLC6A4 (0.47) | OPRK1SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL8295723 | 0.82 | ALDH1A1 (0.46) | LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL1696442 | 0.80 | SLC6A4 (0.50) | OPRK1SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL27778791 | 0.79 | SLC6A4 (0.43) | OPRK1SLC6A4SLC6A2SLC6A3PARP1 | |
| SCHEMBL2260387 | 0.78 | SLC6A4 (0.46) | OPRK1SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL27722327 | 0.76 | SLC6A4 (0.47) | OPRK1SLC6A4SLC6A2SLC6A3LMNA | |
| SCHEMBL436854 | 0.74 | IDO1 (0.50) | SLC6A4SLC6A2SLC6A3LMNAEPHX1 | |
| SCHEMBL19254203 | 0.73 | SLC6A2 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449447-B2 | Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| WO-2005021584-A2 | NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |