Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916636 | 0.87 | SLC6A9 (0.47) | SLC6A9LMNAGAAKDM2BHTT | |
| SCHEMBL23850356 | 0.80 | RAB9A (0.48) | SLC6A9LMNAGAAHTTL3MBTL1 | |
| SCHEMBL31587363 | 0.80 | RAB9A (0.48) | SLC6A9LMNAGAAHTTL3MBTL1 | |
| SCHEMBL31588242 | 0.80 | RAB9A (0.48) | SLC6A9LMNAGAAHTTL3MBTL1 | |
| SCHEMBL23850489 | 0.80 | RAB9A (0.48) | SLC6A9LMNAGAAHTTL3MBTL1 | |
| SCHEMBL23850357 | 0.80 | RAB9A (0.48) | SLC6A9LMNAGAAHTTL3MBTL1 | |
| SCHEMBL3917381 | 0.78 | SLC6A9 (0.77) | SLC6A9 | |
| SCHEMBL23850817 | 0.77 | LMNA (0.65) | LMNAGAAALDH1A1 | |
| SCHEMBL23850205 | 0.77 | LMNA (0.65) | LMNAGAAALDH1A1 | |
| SCHEMBL23850202 | 0.77 | LMNA (0.65) | LMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005023260-A1 | 1- (2-AMINO-BENZOL) -PIPERAZINE DERIVATIVES AS GLYCINE UPTAKE INHIBITORS FOR THE TREATMENT OF PSYCHOSES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-17 | — | — | WO | disclosed |