Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 14/20 | 0.49 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366932 | 0.84 | CRHR1 (0.52) | CRHR1KDM4EALDH1A1F2RL3 | |
| SCHEMBL3363050 | 0.80 | MARS1 (0.50) | CRHR1MARS1 | |
| SCHEMBL3363564 | 0.77 | CRHR1 (0.44) | CRHR1MARS1 | |
| SCHEMBL3367005 | 0.77 | CRHR1 (0.45) | CRHR1MARS1KDM4E | |
| SCHEMBL3364763 | 0.77 | CRHR1 (0.44) | CRHR1MARS1 | |
| SCHEMBL3363623 | 0.76 | CRHR1 (0.42) | CRHR1MARS1 | |
| SCHEMBL3364091 | 0.74 | CRHR1 (0.50) | CRHR1KDM4EALDH1A1F2RL3 | |
| SCHEMBL13538521 | 0.74 | CRHR1 (0.40) | CRHR1KDM4EALDH1A1 | |
| SCHEMBL3843319 | 0.74 | CRHR1 (0.47) | CRHR1KDM4EALDH1A1F2RL3 | |
| SCHEMBL3364854 | 0.71 | CRHR1 (0.56) | CRHR1KDM4EALDH1A1F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016892-A1 | GABANERGIC MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-02-24 | — | — | WO | disclosed |