Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292836 | 0.85 | TACR2 (0.34) | SLC6A4SLC6A3SLC6A2TACR1TACR2 | |
| SCHEMBL8296079 | 0.76 | CCR5 (0.52) | TACR1TACR2TACR3 | |
| SCHEMBL8300821 | 0.73 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2TACR1TACR2 | |
| SCHEMBL8300818 | 0.73 | CCR5 (0.43) | SLC6A4SLC6A3SLC6A2TACR1 | |
| Hydrochloric Acid SCHEMBL8521991 | 0.73 | CCR5 (0.42) | SLC6A4SLC6A3SLC6A2TACR1 | |
| SCHEMBL6957564 | 0.72 | TACR2 (0.54) | TACR1TACR2TACR3 | |
| SCHEMBL6951866 | 0.72 | TACR2 (0.62) | TACR1TACR2TACR3 | |
| SCHEMBL8296291 | 0.72 | TACR1 (0.63) | TACR1TACR2TACR3 | |
| SCHEMBL8366952 | 0.70 | TACR2 (0.47) | TACR1TACR2TACR3 | |
| SCHEMBL8300346 | 0.70 | TACR1 (0.45) | TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512901-B1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-06-23 | — | — | EP | disclosed |
| US-5770735-A | Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1998-06-23 | — | — | US | disclosed |
| US-5625060-A | Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present | Sanofi, Elf (FR) | 1997-04-29 | — | — | US | disclosed |
| US-5340822-A | Substance P, neurokinin antagonists | ELF SANOFI (FR) | 1994-08-23 | — | — | US | disclosed |
| EP-0512901-A1 | Aminated polycyclic compounds and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1992-11-11 | — | — | EP | disclosed |