Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031564 | 0.89 | RAB9A (0.60) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL345717 | 0.87 | RAB9A (0.59) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL20614246 | 0.86 | RAB9A (0.57) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL15649780 | 0.84 | RAB9A (0.56) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL5083291 | 0.84 | GPR35 (0.61) | MAPTKDM4EALDH1A1TTRTDP1 | |
| SCHEMBL10729232 | 0.83 | RAB9A (0.55) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL11158875 | 0.83 | RAB9A (0.55) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL10729189 | 0.82 | GABRA1 (0.65) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL11154751 | 0.82 | RAB9A (0.51) | RAB9AMAPTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL10751886 | 0.81 | RAB9A (0.53) | RAB9AMAPTCYP2D6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244847-B2 | Benzimidazole compounds | ISIS PHARMACEUTICALS, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |