SCHEMBL829784

SCHEMBL829784

O=C(O)C(O)Cc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 1.00
KDM4E B2RXH2 7/20 0.66
HSD17B10 Q99714 6/20 0.66
TDP1 Q9NUW8 6/20 0.66
ALOX15 P16050 5/20 0.66
RECQL P46063 5/20 0.66
HIF1A Q16665 4/20 0.66
USP2 O75604 3/20 0.66
LCK P06239 3/20 0.66
ADORA3 P0DMS8 2/20 0.66
HTR2A P28223 2/20 0.66
PTGS2 P35354 2/20 0.66
FYN P06241 2/20 0.66
EGFR P00533 1/20 0.66
PTGS1 P23219 1/20 0.66
SLC7A5 Q01650 1/20 0.66
PLA2G1B P04054 1/20 0.62
HPGD P15428 5/20 0.55
MAPT P10636 5/20 0.55
POLB P06746 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5691448 1.00 KDM6B (1.00) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29869020 1.00 KDM6B (1.00) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29350434 1.00 KDM6B (1.00) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL18469325 1.00 KDM6B (1.00) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29085430 0.98 KDM6B (0.96) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL6535013 0.98 KDM6B (0.96) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29085429 0.98 KDM6B (0.96) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL19369736 0.85 KDM6B (0.73) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL19369740 0.85 KDM6B (0.73) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL490593 0.84 KDM6B (0.72) KDM6BKDM4EHSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118890971-A Steviol glycoside concentrate and highly soluble steviol glycoside 嘉吉公司 2024-11-01 CN claimed
US-12097231-B2 Steviol glycoside compositions with reduced surface tension CARGILL, INCORPORATED (US) 2024-09-24 US claimed
CN-113710105-B Steviol glycoside solubility enhancers 嘉吉公司 2024-05-28 CN claimed
US-20240074481-A1 CAPSULE-CONTAINING POUCHED PRODUCT FOR ORAL USE REYNOLDS TOBACCO CO R (US) 2024-03-07 US claimed
US-20240050506-A1 STEVIOL GLYCOSIDE COMPOSITIONS WITH REDUCED SURFACE TENSION CARGILL, INCORPORATED (US) 2024-02-15 US claimed
WO-2023177970-A1 STEVIOL GLYCOSIDE CONCENTRATES AND HIGHLY SOLUBLE STEVIOL GLYCOSIDES CARGILL, INCORPORATED (US) 2023-09-21 WO claimed
US-11717549-B2 Steviol glycoside solubility enhancers CARGILL, INCORPORATED (US) 2023-08-08 US claimed
CN-116492359-A Composition containing glycosylated puerarin and preparation method and application thereof 南方医科大学珠江医院 2023-07-28 CN claimed
US-11701400-B2 Steviol glycoside compositions with reduced surface tension CARGILL, INCORPORATED (US) 2023-07-18 US claimed
CN-115403653-A D (+) -beta- (3, 4-dihydroxyphenyl) -lactyl-Pro-Ala-Lys, synthesis and application thereof 首都医科大学 2022-11-29 CN claimed
WO-2004037180-A2 COMPOSITIONS THAT TREAT OR INHIBIT PATHOLOGICAL CONDITIONS ASSOCIATED WITH INFLAMMATORY RESPONSE METAPROTEOMICS, LLC (US) 2004-05-06 WO claimed
US-20030220521-A1 Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension G.D. SEARLE & CO. 2003-11-27 US claimed
US-20030138537-A1 Methods of preparing improved water-soluble extracts containing antioxidants and uses thereof HAUSER, INC. A DELAWARE CORPORATION 2003-07-24 US claimed
WO-2003053148-A1 METHODS OF PREPARING IMPROVED WATER-SOLUBLE EXTRACTS CONTAINING ANTIOXIDANTS AND USES THEREOF HAUSER, INC. (US) 2003-07-03 WO claimed
EP-0484437-A4 RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION SEARLE & CO (US) 1994-06-01 EP claimed
EP-0484437-A1 RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION G.D. Searle & Co. (US) 1992-05-13 EP claimed
WO-1992001667-A1 RENAL-SELECTIVE PRODRUGS FOR CONTROL OF RENAL SYMPATHETIC NERVE ACTIVITY IN THE TREATMENT OF HYPERTENSION G.D. SEARLE & CO. (US) 1992-02-06 WO claimed
US-5011775-A Enzymatic process for the preparation of rosmarinic acid FORSCHUNGSZENTRUM JUELICH GMBH (DE) 1991-04-30 US claimed
WO-1991001724-A1 RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION G.D. SEARLE & CO. (US) 1991-02-21 WO claimed
US-4363815-A Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions YU RUEY J 1982-12-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701400-B2 Steviol glycoside compositions with reduced surface tension STT3A, SIGLEC7, STT3B KDM6B 4245/4885KDM4E 4391/4885HSD17B10 473/4885
US-11717549-B2 Steviol glycoside solubility enhancers SI, TAS2R7, TAS2R31 KDM6B 2458/4885KDM4E 3664/4885HSD17B10 827/4885
US-12097231-B2 Steviol glycoside compositions with reduced surface tension STT3A, SIGLEC7, STT3B KDM6B 4245/4885KDM4E 4391/4885HSD17B10 473/4885
US-20030220521-A1 Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension GLS, APEH, GGH KDM6B 1576/4885KDM4E 1203/4885HSD17B10 268/4885
US-20240050506-A1 STEVIOL GLYCOSIDE COMPOSITIONS WITH REDUCED SURFACE TENSION STT3A, SIGLEC7, STT3B KDM6B 4245/4885KDM4E 4391/4885HSD17B10 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.