Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3496463 | 0.85 | MMP1 (0.43) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL4097244 | 0.84 | MMP1 (0.47) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL5352083 | 0.84 | MMP1 (0.47) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL3910846 | 0.82 | MMP1 (0.46) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL3308160 | 0.82 | ALDH1A1 (0.41) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL5342899 | 0.81 | ALDH1A1 (0.49) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL27366584 | 0.81 | MMP1 (0.45) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL3563381 | 0.81 | MMP1 (0.45) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL525049 | 0.81 | MMP1 (0.45) | MMP1MMP2MMP9MMP12POLB | |
| SCHEMBL1803546 | 0.80 | ALDH1A1 (0.43) | MMP1MMP2MMP9MMP12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3669019-A1 | METHODS AND KITS FOR DETECTING ANTIBIOTIC-INACTIVATING FACTORS | University of Louisville Research Foundation, Inc. (US) | 2020-06-24 | — | — | EP | claimed |
| US-20200172953-A1 | METHODS AND KITS FOR DETECTING ANTIBIOTIC-INACTIVATING FACTORS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. | 2020-06-04 | — | — | US | claimed |
| WO-2004031142-A2 | INHIBITION OF METALLO-BETA-LACTAMASE | TEXAS TECH UNIVERSITY SYSTEM (US) | 2004-04-15 | — | — | WO | claimed |
| WO-2021065099-A1 | COPOLYMER, CURABLE RESIN COMPOSITION, AND CURED PRODUCT | 株式会社ダイセル | 2021-04-08 | — | — | WO | disclosed |
| EP-3669019-A1 | METHODS AND KITS FOR DETECTING ANTIBIOTIC-INACTIVATING FACTORS | University of Louisville Research Foundation, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| US-20200172953-A1 | METHODS AND KITS FOR DETECTING ANTIBIOTIC-INACTIVATING FACTORS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. | 2020-06-04 | — | — | US | disclosed |
| US-8143389-B2 | Inhibiton of metallo-β-lactamase by double-stranded DNA | TEXAS TECH UNIVERSITY (US) | 2012-03-27 | — | — | US | disclosed |
| US-7989613-B2 | isolated polyribonucleotide is used to kill Class B metallo- beta -lactamase producing bacteria; enzyme inhibitor has higher affinity and specificity for binding; with penicillin or cephalosporin; new biodrug for treating bacterial infections | TEXAS TECH UNIVERSITY (US) | 2011-08-02 | — | — | US | disclosed |
| US-20100261777-A1 | Inhibiton of metallo-beta-lactamase by double-stranded dna | TEXAS TECH UNIVERSITY SYSTEM | 2010-10-14 | — | — | US | disclosed |
| US-7772388-B2 | Inhibition of metallo-β-lactamase | TEXAS TECH UNIVERSITY (US) | 2010-08-10 | — | — | US | disclosed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009108055-A1 | WATER SOLUBLE COATING MATERIAL FOR OPTICAL CABLES | DSM IP ASSETS B.V. (NL) | 2009-09-03 | — | — | WO | disclosed |
| US-20090203003-A1 | INHIBITION OF METALLO-BETA-LACTAMASE | TEXAS TECH UNIVERSITY SYSTEM (US) | 2009-08-13 | — | — | US | disclosed |
| US-7456274-B2 | Inhibition of metallo-β-lactamase | TEXAS TECH UNIVERSITY SYSTEM (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080119432-A1 | Inhibition Of Metallo-Beta-Lactamase By Rna | TEXAS TECH UNIVERSITY SYSTEM | 2008-05-22 | — | — | US | disclosed |
| WO-2007025016-A1 | INHIBITION OF METALLO-BETA-LACTAMASE BY DOUBLE-STRANDED DNA | TEXAS TECH UNIVERSITY SYSTEM (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2006135431-A2 | INHIBITION OF METALLO-BETA-LACTAMASE BY RNA | TEXAS TECH UNIVERSITY SYSTEM (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20050202434-A1 | Inhibition of metallo-beta-lactamase | TEXAS TECH UNIVERSITY SYSTEM | 2005-09-15 | — | — | US | disclosed |
| WO-2004031142-A2 | INHIBITION OF METALLO-BETA-LACTAMASE | TEXAS TECH UNIVERSITY SYSTEM (US) | 2004-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119432-A1 | Inhibition Of Metallo-Beta-Lactamase By Rna | RNGTT, EMG1, FBL | MMP1 1074/4885MMP2 223/4885MMP9 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.