SCHEMBL829792

SCHEMBL829792

C[Si](C)(C)c1ccccc1[C]c1ccccc1[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1141374 0.86 APP (0.35) TSHR
SCHEMBL14301518 0.80 TSHR (0.50) TSHR
SCHEMBL716236 0.80 IDO1 (0.31) IDO1TSHR
SCHEMBL7625780 0.80 IDO1 (0.31) IDO1TSHR
SCHEMBL29726936 0.76 IDO1 (0.41) IDO1TSHR
SCHEMBL1880902 0.76 IDO1 (0.41) IDO1TSHR
SCHEMBL563466 0.75 NPC1 (0.50)
SCHEMBL2131460 0.73
SCHEMBL5066300 0.69
SCHEMBL5909513 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP claimed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US claimed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO claimed
EP-2915826-B1 POLYETHYLENE AND PROCESS FOR PRODUCTION THEREOF UNIVATION TECH LLC (US) 2024-02-28 EP disclosed
US-11492425-B2 Metallocene catalyst compositions and polymerization process therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-11-08 US disclosed
US-20210380734-A1 Metallocene Catalyst Compositions and Polymerization Process Therewith EXXONMOBIL CHEMICAL PATENTS INC. 2021-12-09 US disclosed
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US disclosed
US-11059918-B2 Metallocene catalyst compositions and polymerization process therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-07-13 US disclosed
US-11028196-B2 Polyolefin compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-08 US disclosed
EP-3827033-A1 PREPARATION OF BIMODAL RUBBER, THERMOPLASTIC VULCANIZATES, AND ARTICLES MADE THEREFROM ExxonMobil Chemical Patents Inc. (US) 2021-06-02 EP disclosed
US-20210107930-A1 Indacene Based Metallocene Catalysts Useful in the Production of Propylene Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2021-04-15 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492425-B2 Metallocene catalyst compositions and polymerization process therewith TERT, MDM4, PCBP1 IDO1 2018/4885TSHR 4745/4885
US-20210380734-A1 Metallocene Catalyst Compositions and Polymerization Process Therewith TERT, MDM4, PCBP1 IDO1 2018/4885TSHR 4745/4885
US-11059918-B2 Metallocene catalyst compositions and polymerization process therewith TERT, MDM4, PCBP1 IDO1 2018/4885TSHR 4745/4885
US-20210107930-A1 Indacene Based Metallocene Catalysts Useful in the Production of Propylene Polymers INF2, INTS6, PORCN IDO1 31/4885TSHR 4509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.