SCHEMBL563466

SCHEMBL563466

C[Si](C)(C)c1ccccc1C#Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
CYP2C9 P11712 2/20 0.50
HPGD P15428 2/20 0.50
CYP2C19 P33261 2/20 0.50
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 1/20 0.50
APP P05067 1/20 0.50
RAB9A P51151 3/20 0.43
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
GRM5 P41594 7/20 0.42
DHFR P00374 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6754426 0.83 APP (0.55) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL7191185 0.81 NPC1 (0.44) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL1141374 0.81 APP (0.35) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL33721956 0.80 NPC1 (0.43) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL7183857 0.79 NPC1 (0.46) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL2114742 0.77 APP (0.75) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL5871989 0.77 APP (0.75) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL6535646 0.75 NPC1 (0.50) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1
SCHEMBL829792 0.75 IDO1 (0.33)
SCHEMBL7185943 0.72 NPC1 (0.40) NPC1SMN1; SMN2KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3223328-B1 ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF KOLON INC (KR) 2020-07-29 EP claimed
EP-3223328-A1 ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF Kolon Industries, Inc. (KR) 2017-09-27 EP claimed
WO-2013100284-A1 METHOD FOR MANUFACTURING ORGANIC SOLAR CELL AND THE ORGANIC SOLAR CELL MANUFACTURING BY USING THE SAME KOLON INDUSTRIES, INC. (KR) 2013-07-04 WO claimed
US-8216686-B2 Conjugated dendron having no heteroatoms is coupled to the triphenylamine core; organic memory device includes an organic active layer between a first electrode and a second electrode, wherein the organic active layer includes the dendrimer; may be used as a nonvolatile memory SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-07-10 US claimed
US-8124238-B2 Redox system ; dendrimer is connected to core by linker group SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US claimed
US-8044387-B1 Semiconductor device built on plastic substrate SPANSION LLC (US) 2011-10-25 US claimed
US-8012673-B1 Processing a copolymer to form a polymer memory cell SPANSION LLC (US) 2011-09-06 US claimed
US-7902086-B2 Prevention of oxidation of carrier ions to improve memory retention properties of polymer memory cell SPANSION LLC (US) 2011-03-08 US claimed
US-7635859-B2 Memory device including dendrimer SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-12-22 US claimed
US-7632706-B2 System and method for processing an organic memory cell SPANSION LLC (US) 2009-12-15 US claimed
EP-1679720-A2 Memory device including dendrimer Samsung Electronics Co., Ltd (KR) 2006-07-12 EP claimed
US-7026702-B2 Memory device ADVANCED MICRO DEVICES, INC. (US) 2006-04-11 US claimed
WO-2005104188-A2 POLYMER DIELECTRICS FOR MEMORY ELEMENT ARRAY INTERCONNECT ADVANCED MICRO DEVICES, INC. (US) 2005-11-03 WO claimed
US-20050224922-A1 Polymer dielectrics for memory element array interconnect MORGAN STANLEY SENIOR FUNDING, INC. 2005-10-13 US claimed
US-6893895-B1 CuS formation by anodic sulfide passivation of copper surface ADVANCED MICRO DEVICES, INC. (US) 2005-05-17 US claimed
US-20040159835-A1 Memory device CYPRESS SEMICONDUCTOR CORPORATION 2004-08-19 US claimed
US-6768157-B2 Memory device ADVANCED MICRO DEVICES, INC. 2004-07-27 US claimed
US-20040026729-A9 Memory device COATUE CORPORATION 2004-02-12 US claimed
US-20030178667-A1 Memory device CYPRESS SEMICONDUCTOR CORPORATION 2003-09-25 US claimed
US-20030155602-A1 Memory device COATUE CORPORATION 2003-08-21 US claimed