Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.61 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850182 | 0.94 | NR5A1 (0.71) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL4241629 | 0.93 | NR5A1 (0.64) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL15519563 | 0.91 | NR5A1 (0.68) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL15162229 | 0.91 | NR1I2 (0.64) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 | |
| Alcohol SCHEMBL28398877 | 0.90 | LTA4H (0.65) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL555384 | 0.90 | ALDH1A1 (0.56) | LTA4HNR5A1ALDH1A1CYP2D6NR1I2 | |
| SCHEMBL15519209 | 0.89 | NR5A1 (0.71) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL24276581 | 0.88 | PLA2G2A (0.52) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL26850 | 0.87 | LTA4H (0.70) | LTA4HNR5A1CYP3A4SMN1; SMN2CYP2D6 | |
| SCHEMBL19978962 | 0.87 | KDM4E (0.52) | LTA4HNR5A1CYP3A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016885-A2 | COMPOUNDS WITH COMBINED CALCIUM CHANNEL BLOCKER AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITIES FOR TREATMENT OF HEART DISEASE | ARTESIAN THERAPEUTICS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |