Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297149 | 0.90 | PTPN11 (0.34) | NR5A1SOAT1PTPN11PDK2 | |
| SCHEMBL8299021 | 0.88 | NR5A1 (0.37) | NR5A1SOAT1ALDH1A1MAPTHTT | |
| SCHEMBL8297858 | 0.80 | KDM4E (0.40) | NR5A1SOAT1ALDH1A1HTTPTPN11 | |
| SCHEMBL8301789 | 0.79 | NR5A1 (0.36) | NR5A1SOAT1ALDH1A1MAPTATM | |
| SCHEMBL7463536 | 0.76 | NR5A1 (0.42) | NR5A1ALDH1A1LMNAMAPTSMPD1 | |
| SCHEMBL8902280 | 0.73 | SOAT1 (0.39) | SOAT1ALDH1A1MAPTATMPTPN11 | |
| SCHEMBL9169719 | 0.72 | NR5A1 (0.51) | NR5A1ALDH1A1MAPTLTA4HPTPN11 | |
| SCHEMBL9169962 | 0.72 | NR5A1 (0.51) | NR5A1ALDH1A1MAPTLTA4HPTPN11 | |
| SCHEMBL9169123 | 0.72 | NR5A1 (0.51) | NR5A1ALDH1A1MAPTLTA4HPTPN11 | |
| SCHEMBL8299691 | 0.70 | RAB9A (0.44) | NR5A1SOAT1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824522-B1 | 1,8-DIFLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 1999-10-27 | — | — | EP | disclosed |
| US-5882546-A | 1,8-Difluorisoquinoline derivatives and the use thereof in liquid crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |