Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297766 | 0.90 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8299691 | 0.87 | RAB9A (0.44) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8437979 | 0.79 | MAPT (0.38) | MAPTGAAALDH2 | |
| SCHEMBL8298955 | 0.79 | NR5A1 (0.35) | NR5A1MAPTALDH1A1SOAT1PTPN11 | |
| SCHEMBL8298620 | 0.79 | KDM4E (0.47) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7837947 | 0.77 | NR5A1 (0.53) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7842632 | 0.77 | NR5A1 (0.53) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6950774 | 0.75 | NR5A1 (0.45) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6956433 | 0.75 | NR5A1 (0.45) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7841786 | 0.72 | RARB (0.47) | NR5A1RAB9ANPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825987-B1 | 1-FLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5911913-A | 1-fluoroisoquinoline derivatives and the use thereof in liquid crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-06-15 | — | — | US | disclosed |
| EP-0825987-A1 | 1-FLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996035674-A1 | 1-FLUORISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |