SCHEMBL829914

SCHEMBL829914

C=COCCCC(=C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TBXAS1 P24557 2/20 0.33
TET2 Q6N021 3/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2114652 0.94 ALDH1A1 (0.36) ALOX15HSD17B10TBXAS1ALDH1A1CYP3A4
SCHEMBL4914967 0.93 HSD17B10 (0.33) ALOX15HSD17B10TBXAS1ALDH1A1TSHR
SCHEMBL2115013 0.92 ALDH1A1 (0.39) ALOX15HSD17B10TBXAS1ALDH1A1CYP3A4
SCHEMBL2112669 0.92 ALDH1A1 (0.39) ALOX15HSD17B10TBXAS1ALDH1A1CYP3A4
SCHEMBL687329 0.92 ALDH1A1 (0.39) ALOX15HSD17B10TBXAS1ALDH1A1CYP3A4
SCHEMBL2115695 0.89 TSHR (0.34) ALOX15HSD17B10TBXAS1ALDH1A1TSHR
SCHEMBL148736 0.89 TSHR (0.34) ALOX15HSD17B10TBXAS1ALDH1A1TSHR
SCHEMBL133164 0.87 ALOX15 (0.40) ALOX15HSD17B10TET2TET3TET1
SCHEMBL6676912 0.86 CYP2D6 (0.39) ALOX15HSD17B10TBXAS1ALDH1A1TSHR
SCHEMBL5164896 0.83 TBXAS1 (0.33) ALOX15HSD17B10TBXAS1TET2TET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1715945-B1 THICKENING AGENTS SPCM SA (FR) 2015-12-23 EP claimed
US-8242215-B2 Cationic copolymers derived from acrylamides and use thereof S.P.C.M. SA (FR) 2012-08-14 US claimed
US-20100326614-A1 CATIONIC COPOLYMERS DERIVED FROM ACRYLAMIDES AND USE THEREOF SNF S.A.S. (FR) 2010-12-30 US claimed
EP-0835647-B2 Self-foaming cream OREAL (FR) 2010-03-17 EP claimed
US-7532795-B2 Radiation-curable liquid resin composition DSM IP ASSETS B.V. (NL) 2009-05-12 US claimed
JP-2007526367-A 2007-09-13 JP claimed
EP-1715945-A1 THICKENING AGENTS SNF SAS (FR) 2006-11-02 EP claimed
WO-2005079965-A1 THICKENING AGENTS SNF SAS (FR) 2005-09-01 WO claimed
WO-2005053748-A1 NOVEL THICKENING AGENTS HAVING CATIONIC UNITS AND METHOD FOR PREPARING SAME SNF SAS (FR) 2005-06-16 WO claimed
EP-0877591-B1 HAIR CONDITIONING COMPOSITIONS PROCTER & GAMBLE (US) 2002-09-18 EP claimed
EP-0739619-A1 Foaming o/w emulsion based on non-ionic surfactants, a fatty phase and a cross-linked cationic or anionic polymer for topical use L'OREAL (FR) 1996-10-30 EP claimed
EP-0693920-A1 COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN AND PROTECTING THE SKIN FROM UV RADIATION THE PROCTER & GAMBLE COMPANY (US) 1996-01-31 EP claimed
EP-0652774-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER. PROCTER & GAMBLE (US) 1995-05-17 EP claimed
EP-0395282-B1 Thickened aqueous compositions ALLIED COLLOIDS LTD (GB) 1995-03-29 EP claimed
WO-1994023693-A1 COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN AND PROTECTING THE SKIN FROM UV RADIATION THE PROCTER & GAMBLE COMPANY (US) 1994-10-27 WO claimed
EP-0608322-A1 ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS RICHARDSON-VICKS, INC. (US) 1994-08-03 EP claimed
WO-1994002176-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL USE CONTAINING A CROSSLINKED CATIONIC POLYMER AND AN ALKOXYLATED ETHER THE PROCTER & GAMBLE COMPANY (US) 1994-02-03 WO claimed
WO-1993007903-A1 ENHANCED SKIN PENETRATION SYSTEM FOR IMPROVED TOPICAL DELIVERY OF DRUGS RICHARDSON-VICKS, INC. (US) 1993-04-29 WO claimed
US-5100660-A Cationic Polymers ALLIED COLLOIDS LIMITED (GB) 1992-03-31 US claimed
EP-0395282-A2 Thickened aqueous compositions Ciba Specialty Chemicals Water Treatments Limited (GB) 1990-10-31 EP claimed