Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984633 | 0.95 | SMN1; SMN2 (0.44) | GFERFABP4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL496918 | 0.88 | SLC9A1 (0.43) | FABP4SMN1; SMN2FABP3ALDH1A1ALOX15 | |
| SCHEMBL5401523 | 0.80 | PARP1 (0.50) | ALDH1A1ALOX15 | |
| SCHEMBL29226728 | 0.80 | MTNR1A (0.45) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28757986 | 0.79 | PARP1 (0.49) | ALOX15 | |
| SCHEMBL6677783 | 0.78 | TSHR (0.49) | KMT2AALDH1A1 | |
| SCHEMBL7357302 | 0.77 | MTNR1A (0.55) | GFERFABP4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26216592 | 0.76 | TDP1 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL5764412 | 0.76 | MTNR1A (0.43) | — | |
| SCHEMBL1672057 | 0.76 | KDM4E (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000837-A1 | AMINOSULFONYL SUBSTITUTED 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES AS 5HT4-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-06 | — | — | WO | disclosed |