Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638857 | 0.86 | SRC (0.48) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL435044 | 0.86 | SRC (0.48) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL16122568 | 0.84 | ATM (0.45) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL15730605 | 0.82 | ATM (0.43) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL17429815 | 0.78 | GRIN2D (0.45) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL8959908 | 0.77 | GPR84 (0.61) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL30622593 | 0.77 | GPR84 (0.61) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL19708398 | 0.77 | CSNK2A1 (0.53) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL12657284 | 0.76 | ATM (0.54) | PDE4APDE4BPDE4CPDE4DATM | |
| SCHEMBL15255990 | 0.74 | LMNA (0.46) | ATMADRA1AHPGDHSD17B10MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005039617-A1 | USE OF CYCLIC ANABAENOPEPTIN-TYPE PEPTIDES FOR THE TREATMENT OF A CONDITION WHEREIN INHIBITION OF CARBOXYPEPTIDASE U IS BENEFICIAL, NOVEL ANABAENOPEPTIN DERIVATIVES AND INTERMEDIATES THEREOF | ASTRAZENECA AB (SE) | 2005-05-06 | — | — | WO | disclosed |