SCHEMBL8299476

SCHEMBL8299476

Cc1cn([C@@]2(CC(=O)O)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.44
TK1 P04183 5/20 0.41
RNASE1 P07998 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27436150 0.89 TK1 (0.43) TYMPTK1
SCHEMBL14388593 0.89 TK1 (0.43) TYMPTK1
SCHEMBL1517629 0.88 TK1 (0.44) TK1
SCHEMBL887851 0.88 TK1 (0.43) TK1
SCHEMBL28249854 0.87 TK1 (0.42) TK1
SCHEMBL6328412 0.86 TK1 (0.40) TYMPTK1
SCHEMBL4727501 0.85 TK1 (0.41) TK1
Phosphoric Acid SCHEMBL8091428 0.85 TYMP (0.42) TYMPTK1
SCHEMBL1941867 0.85 TK1 (0.41) TK1
SCHEMBL8470852 0.85 TK1 (0.41) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5969135-A COMPOUNDS FOR USE AS ANTISENSE CONTROL OF GENE EXPRESSION AND HYBRIDIZATION ICN PHARMACEUTICALS, INC. (US) 1999-10-19 US disclosed
EP-0789707-A4 AMINO ACID NUCLEIC ACIDS ICN PHARMACEUTICALS (US) 1999-02-24 EP disclosed
EP-0789707-A1 AMINO ACID NUCLEIC ACIDS ICN PHARMACEUTICALS (US) 1997-08-20 EP disclosed
WO-1996014330-A1 AMINO ACID NUCLEIC ACIDS ICNPHARMACEUTICALS (US) 1996-05-17 WO disclosed