Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297257 | 0.71 | MEN1 (0.41) | KDM4ENNMTALDH1A1MEN1IKBKB | |
| SCHEMBL15667001 | 0.68 | UGT2B17 (0.35) | — | |
| SCHEMBL29831950 | 0.68 | UGT2B17 (0.35) | — | |
| SCHEMBL7650362 | 0.65 | PARP1 (0.44) | KDM4EALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL29599524 | 0.65 | HAAO (0.33) | KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL1004219 | 0.63 | KDM4E (0.50) | KDM4ENNMTALDH1A1MAPT | |
| SCHEMBL29521129 | 0.62 | ALDH1A1 (0.42) | KDM4ENNMTALDH1A1MEN1MAPT | |
| SCHEMBL1204023 | 0.62 | PNMT (0.42) | KDM4EALDH1A1MEN1USP2TP53 | |
| SCHEMBL6027899 | 0.62 | KDM4E (0.43) | KDM4ENNMTALDH1A1MEN1MAPT | |
| SCHEMBL23685779 | 0.62 | KDM4E (0.50) | KDM4ENNMTALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000838-A1 | 4-(AMINOMETHYL)-PIPERIDINE BENZAMIDES AS 5HT4-ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-01-06 | — | — | WO | disclosed |