Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173151 | 0.95 | TSHR (0.42) | TSHRCPB1FKBP1AGAAALDH1A1 | |
| SCHEMBL12406849 | 0.90 | TSHR (0.46) | TSHRCPB1FKBP1AALDH1A1MAPK1 | |
| SCHEMBL2171811 | 0.89 | CTSL (0.39) | TSHRCPB1FKBP1AALDH1A1MAPK1 | |
| SCHEMBL13015103 | 0.87 | TSHR (0.44) | TSHRCPB1FKBP1AALDH1A1MAPK1 | |
| SCHEMBL2172914 | 0.81 | ADAM10 (0.44) | TSHRFKBP1AALDH1A1POLBRAB9A | |
| SCHEMBL21984268 | 0.76 | ALDH1A1 (0.55) | TSHRCPB1GAAALDH1A1MAPK1 | |
| SCHEMBL21361580 | 0.76 | ALDH1A1 (0.55) | TSHRCPB1GAAALDH1A1MAPK1 | |
| SCHEMBL20581107 | 0.76 | ALDH1A1 (0.55) | TSHRCPB1GAAALDH1A1MAPK1 | |
| SCHEMBL27709631 | 0.75 | ALDH1A1 (0.60) | TSHRCPB1GAAALDH1A1CA1 | |
| SCHEMBL12282413 | 0.75 | TSHR (0.46) | TSHRCPB1FKBP1AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037826-A1 | SUBSTITUTED CYCLIC HYDROXAMATES AS INHIBITORS OF MATRIX METALLOPROTEINASES | INCYTE CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |