Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299687 | 1.00 | LMNA (0.44) | LMNAKDM4EPDE11APOLBTAS1R3 | |
| SCHEMBL8292270 | 0.90 | PDE11A (0.43) | LMNAKDM4EPDE11AHPGDGAA | |
| SCHEMBL8292266 | 0.90 | PDE11A (0.43) | LMNAKDM4EPDE11AHPGDGAA | |
| SCHEMBL8600133 | 0.84 | LMNA (0.44) | LMNAKDM4EPDE11APOLBTAS1R3 | |
| SCHEMBL8600136 | 0.84 | LMNA (0.44) | LMNAKDM4EPDE11APOLBTAS1R3 | |
| SCHEMBL8566730 | 0.83 | HPGD (0.47) | KDM4EPOLBHPGDTSHRKMT2A | |
| SCHEMBL8301333 | 0.82 | KDM4E (0.46) | LMNAKDM4EPDE11AHPGDGAA | |
| SCHEMBL8301336 | 0.82 | KDM4E (0.46) | LMNAKDM4EPDE11AHPGDGAA | |
| SCHEMBL8603237 | 0.82 | POLB (0.43) | LMNAKDM4EPDE11APOLBSMN1; SMN2 | |
| SCHEMBL8603233 | 0.82 | POLB (0.43) | LMNAKDM4EPDE11APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |