Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 4/20 | 0.43 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600136 | 1.00 | LMNA (0.44) | LMNAKDM4EPDE5APDE11APOLB | |
| SCHEMBL8299688 | 0.84 | LMNA (0.44) | LMNAKDM4EPDE11APOLBTSHR | |
| SCHEMBL8299687 | 0.84 | LMNA (0.44) | LMNAKDM4EPDE11APOLBTSHR | |
| SCHEMBL8603237 | 0.82 | POLB (0.43) | LMNAKDM4EPDE5APDE11APOLB | |
| SCHEMBL8603233 | 0.82 | POLB (0.43) | LMNAKDM4EPDE5APDE11APOLB | |
| SCHEMBL8602155 | 0.81 | POLB (0.49) | LMNAKDM4EPDE11APOLBHTT | |
| SCHEMBL8602151 | 0.81 | POLB (0.49) | LMNAKDM4EPDE11APOLBHTT | |
| SCHEMBL8292906 | 0.79 | PDE5A (0.50) | LMNAPDE5APDE11AHPGDGAA | |
| SCHEMBL8293491 | 0.79 | PDE5A (0.53) | LMNAPDE5APDE11AHPGDGAA | |
| SCHEMBL8292904 | 0.79 | PDE5A (0.50) | LMNAPDE5APDE11AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |