Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297193 | 0.91 | POLB (0.58) | POLBGAAMAPK1MAPTUSP2 | |
| SCHEMBL8291729 | 0.89 | LMNA (0.51) | POLBLMNAMAPK1KMT2ATDP1 | |
| SCHEMBL8436830 | 0.88 | GAA (0.54) | POLBGAALMNAKMT2AHSP90AA1 | |
| SCHEMBL8296702 | 0.83 | TSHR (0.52) | POLBGAALMNAMAPK1MAPT | |
| SCHEMBL8299754 | 0.80 | F10 (0.53) | POLBGAALMNAMAPK1MAPT | |
| SCHEMBL8292507 | 0.79 | HPGD (0.48) | POLBMAPK1MAPTUSP2APEX1 | |
| SCHEMBL8300681 | 0.79 | GAA (0.60) | POLBGAALMNAMAPK1MAPT | |
| SCHEMBL8291728 | 0.79 | HPGD (0.49) | POLBGAALMNAKMT2AALDH1A1 | |
| SCHEMBL8300888 | 0.78 | POLB (0.64) | POLBGAALMNAMAPK1MAPT | |
| SCHEMBL8566730 | 0.77 | HPGD (0.47) | POLBMAPK1MAPTUSP2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |