Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.54 |
| ▸ | MMP3 | P08254 | 15/20 | 0.54 |
| ▸ | MMP7 | P09237 | 14/20 | 0.54 |
| ▸ | MMP1 | P03956 | 12/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714160 | 0.93 | MMP2 (0.63) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL8299410 | 0.90 | MMP2 (0.53) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL8298960 | 0.90 | MMP2 (0.53) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL12714163 | 0.83 | MMP2 (0.62) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL12714162 | 0.83 | MMP2 (0.62) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL8297611 | 0.75 | MMP1 (0.40) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL1609620 | 0.73 | LMNA (0.42) | TDP1LMNATSHR | |
| SCHEMBL15875342 | 0.73 | TDP1 (0.55) | TDP1LMNATSHR | |
| SCHEMBL4424468 | 0.71 | MMP2 (0.86) | MMP2MMP3MMP7MMP1MMP8 | |
| SCHEMBL12714171 | 0.70 | MMP1 (0.48) | MMP2MMP3MMP7MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101537-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LTD (GB) | 2004-11-25 | — | — | WO | disclosed |