Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300090 | 1.00 | EPHX1 (0.36) | EPHX1ACHEALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8539711 | 0.85 | ATM (0.44) | ACHEALDH1A1NPC1ATM | |
| SCHEMBL8539717 | 0.85 | ATM (0.44) | ACHEALDH1A1NPC1ATM | |
| SCHEMBL8544519 | 0.81 | RIPK1 (0.40) | EPHX1DPP4 | |
| SCHEMBL8544522 | 0.81 | RIPK1 (0.40) | EPHX1DPP4 | |
| SCHEMBL2016589 | 0.80 | ALDH1A1 (0.35) | ACHEALDH1A1NPC1USP2POLB | |
| SCHEMBL1074843 | 0.80 | DPP4 (0.33) | SMN1; SMN2DPP4 | |
| SCHEMBL26112742 | 0.80 | DPP4 (0.33) | SMN1; SMN2DPP4 | |
| SCHEMBL1074840 | 0.80 | DPP4 (0.33) | SMN1; SMN2DPP4 | |
| SCHEMBL8303790 | 0.78 | ALDH1A1 (0.35) | ALDH1A1NPC1POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614986-B1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0614986-A1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates and their use as synthesis intermediates | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |