Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292532 | 0.92 | MTNR1A (0.47) | TBXA2RMTNR1AMTNR1BMCHR1NQO2 | |
| SCHEMBL8296298 | 0.86 | MTNR1A (0.44) | TBXA2RMTNR1AMTNR1BMCHR1 | |
| SCHEMBL10405811 | 0.77 | CA1 (0.40) | MCHR1MEN1LMNAKMT2A | |
| SCHEMBL8303981 | 0.77 | MCHR1 (0.40) | DRD3MCHR1MEN1LMNAKMT2A | |
| SCHEMBL8291459 | 0.76 | DRD3 (0.58) | MTNR1AMTNR1BDRD3NAMPT | |
| Hydrochloric Acid SCHEMBL10406133 | 0.76 | CA1 (0.39) | MCHR1MEN1LMNAKMT2A | |
| SCHEMBL8917515 | 0.73 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8114367 | 0.72 | THRA (0.49) | MTNR1AMTNR1B | |
| SCHEMBL8110213 | 0.71 | THRA (0.51) | MTNR1AMTNR1B | |
| SCHEMBL8911962 | 0.69 | DRD3 (0.40) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661273-B1 | Indane derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5686452-A | PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0661273-A1 | Indane derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |