Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CETP | P11597 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17450423 | 0.92 | POLB (0.61) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL13129156 | 0.89 | CETP (0.65) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL28256535 | 0.85 | CETP (0.77) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL28258088 | 0.85 | CETP (0.77) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL12323604 | 0.85 | CETP (0.77) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL21236941 | 0.82 | SMN1; SMN2 (0.60) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL29566038 | 0.81 | HDAC3 (0.59) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL6825065 | 0.81 | P2RX7 (0.72) | KMT2ACETPHDAC3HDAC1HDAC2 | |
| SCHEMBL12316782 | 0.81 | KMT2A (0.66) | KMT2ASMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11725074 | 0.80 | ALDH1A1 (0.60) | CETPHDAC3HDAC1HDAC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108348784-A | Shampoo with cooling feeling compound | 宝洁公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-106279013-A | A kind of method directly being catalyzed and synthesized amide by carboxylic acid and amine | 中国石油大学(北京) | 2017-01-04 | — | — | CN | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |