Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30530733 | 0.98 | LOXL2 (0.48) | F10LOXL2UBE2TPRSS1TMPRSS2 | |
| Hydrochloric Acid SCHEMBL8182776 | 0.98 | LOXL2 (0.48) | F10LOXL2UBE2TPRSS1TMPRSS2 | |
| Hydrochloric Acid SCHEMBL18300378 | 0.98 | LOXL2 (0.48) | F10LOXL2UBE2TPRSS1TMPRSS2 | |
| SCHEMBL12249675 | 0.82 | PRSS1 (0.47) | F10LOXL2UBE2TPRSS1TMPRSS2 | |
| SCHEMBL22120008 | 0.81 | PRMT1 (0.46) | F10UBE2TPRSS1TMPRSS2PRMT1 | |
| SCHEMBL5234177 | 0.80 | NNMT (0.57) | — | |
| SCHEMBL2213651 | 0.79 | HDAC6 (0.36) | F10LOXL2 | |
| SCHEMBL16853368 | 0.78 | RXFP1 (0.41) | MAOA | |
| SCHEMBL14471374 | 0.77 | GAA (0.41) | LMNA | |
| SCHEMBL31906275 | 0.76 | GABRP (0.57) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4216946-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-0925295-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998003503-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-01-29 | — | — | WO | disclosed |