Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445605 | 0.89 | LMNA (0.60) | LMNAHPGDPPARADNMT3AMRGPRX4 | |
| SCHEMBL11445616 | 0.88 | DNMT3A (0.71) | LMNADNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL23657593 | 0.86 | LMNA (0.72) | LMNAHPGDPPARADNMT3AHDAC1 | |
| SCHEMBL11464602 | 0.85 | PTGER4 (0.69) | LMNAHPGDPPARADNMT3AHDAC1 | |
| SCHEMBL11516368 | 0.84 | LMNA (0.68) | LMNAHPGDPPARADNMT3AHDAC1 | |
| SCHEMBL11356211 | 0.83 | LMNA (0.64) | LMNAHPGDPPARADNMT3AHDAC1 | |
| SCHEMBL11445783 | 0.81 | CA1 (0.57) | LMNAHPGDMRGPRX4APEX1ALDH1A1 | |
| SCHEMBL11488803 | 0.81 | PPARA (0.67) | LMNAPPARADNMT3AHDAC1HDAC6 | |
| SCHEMBL13812752 | 0.80 | LMNA (0.60) | LMNAHPGDPPARADNMT3AAPEX1 | |
| SCHEMBL29617795 | 0.80 | LMNA (0.62) | LMNAHPGDPPARADNMT3AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182775-A | Benzoic acids and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-08 | — | — | US | disclosed |