Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334504 | 0.87 | GAA (0.54) | NOTUMGAAMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6775779 | 0.86 | GAA (0.53) | NOTUMGAAMEN1KMT2ALMNA | |
| SCHEMBL7106084 | 0.76 | NOTUM (0.41) | NOTUMHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL8332662 | 0.73 | MAPT (0.42) | NOTUMHTR2AHTR2CLMNACYP3A4 | |
| SCHEMBL8522982 | 0.72 | ALDH1A1 (0.41) | NOTUMHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL8524737 | 0.72 | MAPT (0.43) | NOTUMHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL8331768 | 0.72 | ALDH1A1 (0.57) | HTR2CMEN1KMT2ALMNAP2RY1 | |
| SCHEMBL8334232 | 0.69 | XPO1 (0.39) | NOTUMHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL7552151 | 0.69 | NOTUM (0.63) | NOTUMHTR2AHTR2CMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6774819 | 0.68 | XPO1 (0.39) | NOTUMHTR2AHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925300-A4 | — | — | 1999-06-30 | — | — | EP | claimed |
| EP-0925300-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-30 | — | — | EP | claimed |
| WO-1997030054-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-08-21 | — | — | WO | claimed |