Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6774819 | 0.99 | XPO1 (0.39) | XPO1HTR2AHTR2CCNR2CCKBR | |
| SCHEMBL8332799 | 0.75 | ALDH1A1 (0.40) | HTR2AHTR2CCNR2ALDH1A1MAPT | |
| SCHEMBL8337181 | 0.75 | ALDH1A1 (0.40) | HTR2AHTR2CCNR2P2RX1MEN1 | |
| SCHEMBL6775028 | 0.75 | SIGMAR1 (0.50) | MEN1KMT2AALDH1A1MAPTNOTUM | |
| Hydrochloric Acid SCHEMBL6769802 | 0.74 | ALDH1A1 (0.41) | HTR2AHTR2CHDAC1HDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL6774822 | 0.74 | CNR2 (0.37) | XPO1HTR2AHTR2CCNR2CPT2 | |
| SCHEMBL7743748 | 0.73 | ALDH1A1 (0.39) | HTR2AHTR2CCNR2FGFR4ERAP1 | |
| SCHEMBL331761 | 0.72 | PDK1 (0.52) | HTR2AHTR2CCNR2MEN1KMT2A | |
| SCHEMBL27544652 | 0.70 | CNR2 (0.53) | HTR2AHTR2CCNR2CPT2CPT1A | |
| SCHEMBL10241674 | 0.69 | NOTUM (0.66) | HTR2AHTR2CCNR2XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |