Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524737 | 0.89 | MAPT (0.43) | ALDH1A1MAPTTP53NOTUMLMNA | |
| SCHEMBL8332662 | 0.81 | MAPT (0.42) | ALDH1A1MAPTTP53NOTUMLMNA | |
| SCHEMBL8337181 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTTP53LMNAPOLB | |
| SCHEMBL8332799 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTTP53LMNAPOLB | |
| Hydrochloric Acid SCHEMBL6769802 | 0.73 | ALDH1A1 (0.41) | ALDH1A1MAPTTP53LMNAPOLB | |
| SCHEMBL8332741 | 0.72 | SIGMAR1 (0.47) | MAPTNOTUMLMNAMEN1KMT2A | |
| SCHEMBL7743748 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTTP53LMNAPOLB | |
| SCHEMBL8300934 | 0.72 | NOTUM (0.41) | MAPTTP53NOTUMLMNAHTR2A | |
| SCHEMBL7552151 | 0.68 | NOTUM (0.63) | NOTUMLMNAHTR2AHTR2CMEN1 | |
| SCHEMBL24011079 | 0.67 | NOTUM (0.84) | ALDH1A1MAPTTP53NOTUMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |