Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182066 | 0.86 | L3MBTL1 (0.73) | L3MBTL1ALDH1A1GAAAKR1C3HTT | |
| SCHEMBL218541 | 0.86 | HTR3E (0.61) | L3MBTL1ALDH1A1GAAAKR1C3KMT2A | |
| SCHEMBL2093519 | 0.80 | HTR3E (0.54) | L3MBTL1ALDH1A1GAAKMT2AHTR3E | |
| SCHEMBL8301012 | 0.77 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1GAAAKR1C3HTT | |
| SCHEMBL19049426 | 0.75 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1GAAAKR1C3HTT | |
| SCHEMBL2094842 | 0.75 | HPGD (0.73) | L3MBTL1ALDH1A1GAADRD3LMNA | |
| SCHEMBL27976453 | 0.74 | AKR1C3 (0.85) | L3MBTL1ALDH1A1GAAAKR1C3HTT | |
| SCHEMBL19049598 | 0.73 | GFER (0.56) | L3MBTL1ALDH1A1GAAAKR1C3HTT | |
| SCHEMBL632352 | 0.73 | L3MBTL1 (0.73) | L3MBTL1ALDH1A1GAAAKR1C3HTT | |
| SCHEMBL29656856 | 0.73 | HTR3E (0.73) | L3MBTL1ALDH1A1GAAAKR1C3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598046-B1 | CYCLIC UREAS USEFUL AS ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | PROCTER & GAMBLE PHARMA (US) | 1999-03-24 | — | — | EP | claimed |