Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4182066 | 0.77 | L3MBTL1 (0.73) | L3MBTL1AKR1C3ALDH1A1GAAMAPT | |
| SCHEMBL9271170 | 0.77 | SLC18A3 (0.44) | L3MBTL1AKR1C3ALDH1A1SLC18A3MAPT | |
| SCHEMBL8301010 | 0.77 | L3MBTL1 (0.56) | L3MBTL1AKR1C3ALDH1A1GAAMAPT | |
| SCHEMBL6344083 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1SLC18A3MAPTSMN1; SMN2FAAH | |
| SCHEMBL19049426 | 0.70 | L3MBTL1 (0.71) | L3MBTL1AKR1C3ALDH1A1GAAMAPT | |
| SCHEMBL27976453 | 0.70 | AKR1C3 (0.85) | L3MBTL1AKR1C3ALDH1A1GAAMAPT | |
| SCHEMBL6960504 | 0.69 | SIGMAR1 (0.56) | L3MBTL1ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL29656856 | 0.69 | HTR3E (0.73) | L3MBTL1AKR1C3ALDH1A1GAASLC18A3 | |
| SCHEMBL28599511 | 0.69 | HTR3E (0.73) | L3MBTL1AKR1C3ALDH1A1GAASLC18A3 | |
| SCHEMBL632352 | 0.69 | L3MBTL1 (0.73) | L3MBTL1AKR1C3ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598046-B1 | CYCLIC UREAS USEFUL AS ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | PROCTER & GAMBLE PHARMA (US) | 1999-03-24 | — | — | EP | claimed |