Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908785 | 0.74 | MEN1 (0.42) | MTNR1BCYP1A2TSHRMTNR1AMEN1 | |
| SCHEMBL8298174 | 0.73 | GRM7 (0.41) | MTNR1BMTNR1A | |
| SCHEMBL9489863 | 0.72 | MTNR1A (0.46) | MTNR1BCYP1A2TSHRMTNR1AMEN1 | |
| SCHEMBL8296922 | 0.72 | PYGL (0.41) | MTNR1BCYP1A2TSHRMTNR1AMEN1 | |
| SCHEMBL8298173 | 0.71 | PPARA (0.53) | PPARA | |
| SCHEMBL16770603 | 0.70 | SIGMAR1 (0.39) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL464668 | 0.70 | SIGMAR1 (0.39) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL22768719 | 0.70 | SIGMAR1 (0.39) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL16770602 | 0.70 | SIGMAR1 (0.39) | MTNR1BMTNR1ASIGMAR1 | |
| SCHEMBL13616986 | 0.70 | SIGMAR1 (0.39) | MTNR1BMTNR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661273-B1 | Indane derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5686452-A | PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0661273-A1 | Indane derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |