Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432548 | 0.84 | ADRB2 (0.46) | HDAC1HDAC2HDAC8HSP90AA1HSP90AB1 | |
| SCHEMBL3717795 | 0.82 | ALDH1A1 (0.47) | TSHRHSD17B10CA2THRATHRB | |
| SCHEMBL3720465 | 0.81 | SMN1; SMN2 (0.46) | HDAC1HDAC2HDAC8THRATHRB | |
| SCHEMBL340041 | 0.80 | HDAC1 (0.42) | HDAC1HDAC2HDAC8ACACBMAPT | |
| SCHEMBL19962980 | 0.79 | MAOB (0.39) | THRATHRBACACBPTGDRMEN1 | |
| SCHEMBL19962979 | 0.79 | MAOB (0.39) | THRATHRBACACBPTGDRMEN1 | |
| SCHEMBL757118 | 0.79 | FFAR4 (0.43) | TSHRHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL9856358 | 0.79 | SHBG (0.46) | HDAC1HDAC2HDAC8ACACBMAPT | |
| SCHEMBL27590184 | 0.78 | GAA (0.44) | HSP90AA1HSP90AB1CA2THRATHRB | |
| SCHEMBL27540583 | 0.77 | PPARG (0.46) | TSHRHSD17B10ACACBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661281-B1 | Substituted phenylethers as pesticides | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | disclosed |
| US-5663379-A | AGROCHEMICAL ACTIVE INGREDIENTS | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0504812-B1 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL CO (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0661281-A1 | Substituted phenylethers as pesticides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| US-5302619-A | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5262441-A | APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0504812-A2 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-23 | — | — | EP | disclosed |