Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663381 | 0.91 | RAB9A (0.59) | MEN1KMT2APTPN1MAPTLMNA | |
| SCHEMBL18147991 | 0.87 | MEN1 (0.67) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL1455800 | 0.87 | KMT2A (0.73) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL8303947 | 0.85 | ALDH1A1 (0.71) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL4728442 | 0.85 | NPC1 (0.58) | MEN1KMT2AMAPTPOLBTDP1 | |
| SCHEMBL1665798 | 0.82 | MAPT (0.59) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL14221428 | 0.82 | KMT2A (0.59) | MEN1KMT2AMAPTPOLBRAB9A | |
| SCHEMBL25394468 | 0.81 | MEN1 (0.58) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL8711539 | 0.80 | KMT2A (0.71) | MEN1KMT2AGAAPTPN1MAPT | |
| SCHEMBL7142315 | 0.80 | KMT2A (0.71) | MEN1KMT2AGAAPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |