Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567528 | 0.86 | HSD17B10 (0.66) | HSD17B10HPGDKDM4ETSHRNPSR1 | |
| SCHEMBL8568497 | 0.84 | KDM1A (0.49) | HPGDROCK2KMT2AMEN1MAPT | |
| SCHEMBL8301379 | 0.83 | HSD17B10 (0.69) | HSD17B10HPGDKDM4ETSHRNPSR1 | |
| SCHEMBL8297761 | 0.82 | HSD17B10 (0.69) | HSD17B10HPGDKDM4ETSHRNPSR1 | |
| SCHEMBL8301638 | 0.81 | PKM (0.56) | PKMHPGDKDM4ETSHRROCK2 | |
| SCHEMBL8297954 | 0.80 | PKM (0.68) | PKMHPGDHSP90AA1KMT2AMEN1 | |
| SCHEMBL9231471 | 0.79 | HSD17B10 (0.59) | HSD17B10PKMHPGDKDM4ETSHR | |
| SCHEMBL8293174 | 0.75 | TSHR (0.56) | HSD17B10PKMHPGDKDM4ETSHR | |
| SCHEMBL5338096 | 0.74 | PKM (0.77) | PKMHPGDROCK2ROCK1HSP90AA1 | |
| SCHEMBL8292899 | 0.73 | ALDH1A1 (0.50) | HPGDNPSR1ROCK2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686625-B1 | ANTHRANILIC ACID DERIVATIVE | EISAI CO LTD (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5716993-A | PHOSPHODIESTERASE ENZYME INHIBITOR FOR TREATING CARDIOVASCULAR DISORDER, ANGINA PECTORIS, HYPERTENSION, ASTHMA | EISAI CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0686625-A1 | ANTHRANILIC ACID DERIVATIVE | Eisai Co., Ltd. (JP) | 1995-12-13 | — | — | EP | disclosed |