SCHEMBL8301562

SCHEMBL8301562

O=C(c1ccc(O)cc1)c1cc(-n2nc3ccccc3n2)c(O)c(-n2nc3ccccc3n2)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.42
RAB9A P51151 5/20 0.41
NPC1 O15118 4/20 0.41
POLB P06746 3/20 0.40
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 5/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
GAA P10253 2/20 0.37
USP2 O75604 1/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MAPT P10636 5/20 0.36
HTT P42858 2/20 0.36
HPGD P15428 2/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
PKM P14618 1/20 0.36
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418498 0.92 NPC1 (0.43) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL9418500 0.83 ALDH1A1 (0.37) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL2553971 0.81 NPC1 (0.48) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL14255449 0.77 MEN1 (0.46) RAB9ANPC1ALDH1A1SMN1; SMN2LMNA
SCHEMBL1263997 0.75 NPC1 (0.58) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL14155871 0.72 KDM4E (0.36) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL1263980 0.72 NPC1 (0.42) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL1264052 0.72 BCL2 (0.49) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL1263991 0.70 NPC1 (0.40) RAB9ANPC1POLBALDH1A1SMN1; SMN2
SCHEMBL1262808 0.69 NPC1 (0.54) RAB9ANPC1POLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0431868-B1 Bis(benzotriazolyl)benzophenones and their use as UV absorbers IOPTEX RESEARCH INC (US) 1994-09-21 EP claimed
JP-4117368-A None JP disclosed
EP-0764686-B1 Hybrid s-triazine light stabilizers substituted by benzotriazole or benzophenone moieties and compositions stabilized therewith CIBA GEIGY AG (CH) 1999-06-16 EP disclosed
EP-0764686-A1 Hybrid s-triazine light stabilizers substituted by benzotriazole or benzophenone moieties and compositions stabilized therewith Ciba SC Holding AG (CH) 1997-03-26 EP disclosed
US-5585422-A PROTECT POLYMERS FROM DELETERIOUS EFFECTS OF ACTINIC RADIATION AS WELL AS GOOD RESISTANCE TO LOSS BY VOLATILIZATION DURING PROCESSING CIBA-GEIGY CORPORATION (US) 1996-12-17 US disclosed
EP-0431868-B1 Bis(benzotriazolyl)benzophenones and their use as UV absorbers IOPTEX RESEARCH INC (US) 1994-09-21 EP disclosed
US-5194456-A For intraocular/contact lenses and eyeglasses with lenses of polycarbonates IOPTEX RESEARCH, INC. (US) 1993-03-16 US disclosed
JP-H04117368-A UV ABSORBER AND MATERIAL CONTAINING SUCH ABSORBER IOPTEX RES INC 1992-04-17 JP disclosed