Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418498 | 0.82 | NPC1 (0.43) | MEN1KMT2AGAAUSP2KEAP1 | |
| SCHEMBL14255450 | 0.78 | PTGES (0.49) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL8301562 | 0.77 | LIG1 (0.42) | MEN1KMT2AGAAUSP2KEAP1 | |
| SCHEMBL1263997 | 0.73 | NPC1 (0.58) | ALDH1A1HPGDLMNAKDM4ETDP1 | |
| SCHEMBL2802927 | 0.72 | NPC1 (0.49) | MEN1KMT2AGAAALDH1A1HPGD | |
| Benzophenone SCHEMBL8429418 | 0.72 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL7089753 | 0.72 | NPC1 (0.59) | ALDH1A1HPGDLMNACYP1A2CYP2C19 | |
| SCHEMBL14462716 | 0.69 | NPC1 (0.50) | MEN1KMT2AGAAUSP2ALDH1A1 | |
| SCHEMBL8861243 | 0.69 | MEN1 (0.70) | MEN1KMT2AGAAUSP2KEAP1 | |
| SCHEMBL28021862 | 0.69 | MEN1 (0.75) | MEN1KMT2AGAAUSP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1900743-A1 | Organosilyl-Benzo-triazole derivatives, processes for their production and their use as UV protecting agents | ISDIN, S.A. (ES) | 2008-03-19 | — | — | EP | disclosed |
| EP-1894936-A1 | Organosilyl-Benzo-triazole derivatives, processes for their production and their use as UV protecting agents | ISDIN, S.A. (ES) | 2008-03-05 | — | — | EP | disclosed |