Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884145 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1RAB9AMAPK1MEN1 | |
| SCHEMBL27175314 | 0.76 | MEN1 (0.40) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL26922085 | 0.72 | KCNH2 (0.42) | CYP3A4HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL25278969 | 0.71 | KCNH2 (0.41) | MEN1KMT2ACYP3A4 | |
| SCHEMBL30040451 | 0.70 | CYP3A4 (0.59) | KDM4EALDH1A1RAB9ACYP3A4MAPT | |
| SCHEMBL1705264 | 0.70 | CYP3A4 (0.59) | KDM4EALDH1A1RAB9ACYP3A4MAPT | |
| SCHEMBL30496378 | 0.70 | PNMT (0.43) | GAAL3MBTL1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL31193341 | 0.68 | CYP3A4 (0.56) | KDM4EALDH1A1RAB9ACYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL9871800 | 0.68 | CYP3A4 (0.56) | KDM4EALDH1A1RAB9ACYP3A4MAPT | |
| SCHEMBL30297520 | 0.67 | HTR2A (0.42) | ALOX12HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037779-A2 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS USED FOR FUNCTIONALLY INFLUENCING DIFFERENT CELLS AND TREATING IMMUNOLOGICAL, INFLAMMATORY, NEURONAL, AND OTHER DISEASES | IMTM GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |