Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978380 | 0.78 | PKM (0.35) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL3665720 | 0.73 | PKM (0.45) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL16571690 | 0.70 | PKM (0.42) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL3402649 | 0.67 | PKM (0.36) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL9747384 | 0.66 | TSHR (0.36) | ALDH1A1MAPT | |
| SCHEMBL3047206 | 0.66 | — | — | |
| SCHEMBL7333555 | 0.65 | PKM (0.35) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL7421934 | 0.65 | PKM (0.35) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL7295778 | 0.65 | PKM (0.35) | PKMKDM4ETHRBHTTALDH1A1 | |
| SCHEMBL7304285 | 0.65 | PKM (0.35) | PKMKDM4ETHRBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900224-A1 | PROPAGYLGLYCINE DERIVATIVES, PREPARATION AND UTILISATION THEREOF AS SYNTHESIS INTERMEDIATES | SYNTHELABO (FR) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040052-A1 | PROPAGYLGLYCINE DERIVATIVES, PREPARATION AND UTILISATION THEREOF AS SYNTHESIS INTERMEDIATES | SYNTHELABO (FR) | 1997-10-30 | — | — | WO | disclosed |